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Ceriello A, Novials A, Canivell S, La Sala L, Pujadas G, Esposito K, Testa R, Bucciarelli L, Rondinelli M, Genovese S: Simultaneous GLP-1 and insulin administration acutely enhances their vasodilatory, antiinflammatory, and antioxidant action in type 2 diabetes

BPC-157's specificity for the inflammatory iNOS isoform preserves protective vascular NO while reducing the contractility-blocking excess

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For those unfamiliar with why this happens, the discomfort can feel alarming and lead to premature discontinuation of an otherwise well-designed protocol

We appreciate the funding support from National Heart Blood Lung Institute at the National Institutes of Health (NIH) award 1R15HL143545-01A1