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Pain may come from tendinopathy, partial tearing, joint instability, nerve irritation, referred pain, inflammatory disease, poor movement mechanics, overtraining, inadequate recovery, or an unresolved structural issue

In pregnancy, a lack of folate can lead to pregnancy loss and neural tube defects, and has also been linked to a higher risk of behavioural disorders such as autism and ADHD

When taking oral semaglutide, some people may experience common side effects such as nausea, vomiting, and diarrhea

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1 Introduction Bone defects are commonly encountered in clinical practice and can arise from various causes, including trauma (e.g., fractures), age-related bone loss (e.g., osteoporosis), infections (e.g., osteomyelitis and periodontitis), cancer (e.g., surgical resection), genetic diseases (e.g., inherited bone marrow failure syndrome), and congenital defects (e.g., cleft palate)