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Others reported reduced drinking

These hepatocytes coordinate their functions with non-parenchymal cell types, including cholangiocytes, endothelial cells, Kupffer cells, immune cells and hepatic stellate cells 5

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Leptin regulates sugar and amino acids transport in the human intestinal cell line C aco2

There are different types of variants they can be non-problem causing (benign), disease-causing (pathogenic) or of unknown significance