10.1056/NEJMoa2032183 90 YangJ.RenJ.SongJ.LiuF.WuC.WangX.et al (2013)
The trials were originally met with limited enthusiasm since several extensive outcome trials had indicated that intensified diabetes therapy was not associated with cardiovascular benefit
Rare, More Serious Side Effects Anecdotal Side Effects There has also been plenty of media buzz about anecdotal side effects with names like Ozempic face and Ozempic butt. These cosmetic side effects arent unhealthy, and arent directly caused by GLP-1s
Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study
Oral GLP-1 therapies are viewed as a major future growth segment because they can improve access and reduce injection-related barriers
124,125,126 The design concept of these multi-agonists is to simultaneously regulate multiple key metabolic pathways to achieve more effective control over blood sugar, body weight, and overall metabolic health
