73 People with non-proliferative diabetic retinopathy requiring acute therapy, proliferative diabetic retinopathy and macular edema have not been studied in the SURPASS program and for these patients tirzepatide should be used with caution and appropriate monitoring
What the published research reported A phase-2 randomized trial published in the New England Journal of Medicine in 2023 studied retatrutide in adults with obesity and reported substantial, dose-dependent reductions in body weight over 48 weeks, alongside a gastrointestinal side-effect profile broadly similar to other incretin drugs
(PubMed) Pettegrew JW, Klunk WE, Panchalingam K, Kanfer JN, McClure RJ
Translational andrology and urology , 9 (Suppl 2), S149S159
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J., Ridder, A