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The basic mechanism of tissue injury is attributed to viral binding to angiotensin-converting enzyme 2 (ACE2) receptors located on several different human cells

Figure 2 These articles were conducted in 17 LAC countries/territories: 7 from the Caribbean, 7 from South America, and 3 from Central America

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Future research should focus on identifying optimal therapeutic combinations and addressing unmet needs in underrepresented and high-risk patient groups

P.HolscherC.et al (2021)