Pernicious anaemia, atrophic gastritis, proton pump inhibitors, metformin, and gastrointestinal surgery significantly impair B12 absorption
Afferent vagus nerve signalling has a primary role in informing the brain about the presence of peripheral inflammation during exposure to low levels of proinflammatory stimuli
#Zasocitinib: A novel oral therapy for plaque psoriasis developed with AI that just succeeded in late-stage studies and plans regulatory filings in 2026
Its active ingredient, semaglutide , has also demonstrated significant effectiveness for weight loss, making it widely used off-label and in related formulations for obesity management
However, this proportion is identical to weight loss without medication
Nicholls: Well, I think were trying to understand the benefits of these agents across a whole range of different end organ complications