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It blocks HIV expression in acute and chronic infection models, and HIV replication in normal peripheral blood mononuclear cells

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The Journal of Neural Transmission 2003

doi: 10.1016/j.jhep.2021.03.014 59

Genetically modified folate overproducing strains of some fungi and bacteria have been constructed, e.g., Ashbya gossypii , Escherichia coli , and Bacillus subtilis , the first being the best folate producer reported to date with folate titers of 6.6 mg/L (i.e., 146-fold higher than the wild strain) 631,632,633,634