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No specific human trials in optic neuritis

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Therapeutic potential of resveratrol: the in vivo evidence

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More specifically, inhibition of NF-B by Nrf2, as previously discussed, reduces the expression of pro-inflammatory cytokines such as tumour necrosis factor- (TNF), interleukines IL1, IL6, IL8 as well as the NF-B-mediated processes including epithelial to mesenchymal transition [47] and tumour vascularization via upregulation of vascular endothelial growth factor (VEGF) and its receptors [48]

However, the inability of the 295422 receptor to rescue baseline transcription (Fig