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Keywords: Chronic spontaneous urticaria, GLP-1 receptor agonists, Semaglutide, Tirzepatide, Immunomodulation, Metabolic inflammation Key Summary Points Introduction Chronic spontaneous urticaria (CSU) is characterized by mast cell degranulation leading to the recurrent appearance of wheals lasting for more than 6 weeks
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Although cell signaling studies are desirable for further evaluation of SR18 for obvious reasons, as an alternative, the agonistic potential of SR18 was preliminarily evaluated using computational structural biology techniques instead
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