Sun K, Shi Y, Yan C, Wang S, Han L, Li F, Xu X, Wang Y, Sun J, Kang Z, et al
The disconnect between preclinical efficacy and human clinical outcomes remains unexplained and represents a significant limitation for potential therapeutic applications
The mechanism for this has been observed in rat brain mitochondria
Effects of ozone on daily mortality have been detected even when study days are restricted to those with a 24-hour average ozone concentration below 60 ppb (approximately equivalent to an 8-hour average below 90 ppb)
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