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Science 252:1848-1851

This extended pharmacokinetic profile makes it particularly suitable for long-term metabolic research studies [2]

Benefits: It supports fetal development during pregnancy, aids in red blood cell production, and helps prevent certain birth defects

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An important limitation of the present study is the substantial imbalance in case numbers across ancestry groups: European ancestry participants (2,302 cases) comprise the largest group, followed by African ancestry (1,339 cases), with considerably fewer cases among Admixed American/Latino participants (465 cases)