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Human DNA-dependent protein kinase activation mechanism

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In our approach based on the concentration-effect relationships, we did not account for all possible confounding factors known to influence lactate clearance

POMC-derived peptides, particularly -MSH, stimulate MC1R of melanocytes, releasing the intracellular second messenger cAMP, which in turn induces a cascade of intracellular molecular events, ultimately activating the microphthalmia-associated transcription factor (MITF)

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Ketter, T.A