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2.6.2 Supportive Secondary Endpoints Supportive secondary physical fitness endpoints included: self-reported physical functioning (Short Form 36 Health Survey)

Conclusion: Rats on the fcHF diet show stronger food intake inhibition to the melanocortin receptor agonist MTII than rats on the CHOW, fcHS, and fcHFHS diet, which is independent of caloric intake and body weight gain

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Metabolic Shift Metabolic rate tends to decrease after discontinuing GLP1, such that the body expends fewer kilojoules in resting and active states

This is more common in people who eat very early dinners, skip evening snacks, or take insulin or certain diabetes medications

The article points to people with a personal or family history of migraines, baseline hypertension, or dehydration-sensitive conditions