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NAC can promote osteogenic differentiation of PDLSCs and facilitate bone formation on the tension side by reducing the excessive ROS generated by cyclic stress, enabling NAC to potentially improve bone remodeling and reduce adverse effects of orthodontics (Xi et al., 2022)

When it is overactive, as in autoimmune disease, it promotes regulatory pathways that calm the response

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GLP-1 increases insulin release from the pancreas, but only in response to elevated blood sugars

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