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J Psychiatr Res 41(6):472480

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If left untreated, a B12 deficiency can cause more severe health problems, including nerve damage, cognitive issues, and anaemia

Moreover, glycyrrhizin was found to protect melanocytes from oxidative stress by inducing the nuclear translocation of Nrf2 in human melanocytes, thus inducing the expression of HO-1, an antioxidant enzyme responsible for heme degradation [81]

Its also a precursor to glutathione producing cysteine through the transsulfuration pathway

However, the choice of such cosolvents and solvents can significantly influence the effective bioavailable concentration of the compound, thereby affecting pharmacokinetic and pharmacodynamic outcomes