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This allows faster results and higher antioxidant levels, especially for patients with gut inflammation or poor nutrient absorption

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All volunteers gave written informed consent before participation in this study

The decision to terminate the clinical development of Lotiglipron was based on the pharmacokinetic data from the clinical Phase 1 drug-drug interaction studies (NCT05671653 and NCT05788328), as well as the laboratory measurements of elevated transaminases in these Phase 1 studies and the ongoing Phase 2 study (NCT05579977)