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Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes

Serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) peaked at 12 h in both mice genotypes (Figures 2a and b)

Immunogenicity of BYDUREON in Pediatric Patients In a 52-week BYDUREON trial (24-week controlled and 28-week extended treatment period) for the improvement of glycemic control in pediatric patients with type 2 diabetes mellitus (Trial 9) [see Clinical Studies (14.6)], 37/58 (64%) of BYDUREON-treated patients had high titer anti-exenatide antibodies (high titer was defined as 625) at any time during the study

As such, tirzepatide is anticipated to receive marketing approval by mid-to-late 2022

Nat Biotechnol 19:940945

Anatomic Sites and ICD-10-CM Location Mapping Small intestine (K50.0x): Includes duodenum, jejunum, and ileum