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Published research demonstrates that Matrixyls effect is concentration-dependent and time-limited once fibroblasts have adequately responded to the matrikine signal, the collagen production response attenuates without additional stimulation from other growth factors

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Serious adverse events were uncommon, and no hepatotoxic signals emerged over the 48-week study period

[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Ben Mihoub A., Acherar S., Frochot C., Malaplate C., Yen F.T., Arab-Tehrany E

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