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In addition to sleep disorders, valerian has been used for gastrointestinal spasms and distress, epileptic seizures, and attention deficit hyperactivity disorder

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Candidates are generally adults with diagnosed hormonal imbalances, such as PCOS and hypothalamic amenorrhea, who have failed standard treatments

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doi: 10.1016/j.fct.2013.04.053

Pickart and Margolina's 2018 review catalogued over 4,000 human genes reportedly modulated by GHK-Cu exposure, including upregulation of collagen synthesis genes (COL1A1, COL4A1), matrix metalloproteinase regulators, and antioxidant enzymes [11]