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Instrument-assisted soft tissue techniques include Astym therapy, which increased fibroblast activation and number, production of fibronectin, movement, and decreased pain in patients with fibrosis (129) and Graston technique which reduces pain and improves movement (130), and are performed by physical therapists who can be located on websites for these techniques

Med Hypotheses 143 , 110185 (2020)

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Human studies indicate that the insulinotropic action of GIP is blunted in individuals with severe hyperglycemia, in contrast to the intact action of GLP-1

Moreover, muscle biopsies from older athletic participants showed improved mitochondrial respiration compared to age-matched and physically impaired participants 331