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Reported side effects are rare and generally mild: Temporary lethargy Mild swelling or irritation at the injection site Occasional digestive upset (less common with injectable forms) One area of caution: dogs with active cancer

That said, were not in the business of locking anyone into long-term contracts

Chemokine Receptor CCR1 Antagonist CCX354-C Treatment for Rheumatoid Arthritis: CARAT-2, a Randomised, Placebo Controlled Clinical Trial

What they found (summary): Amylin acts primarily in the area postrema , lesioning the area postrema abolishes the anorexigenic effect of amylin Acute vs chronic effect: acute, suppression of feeding

That does not make the topic meaningless, but it does mean claims should be careful

UTIs, presumably due to reduced immune cell function