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Holding the bottle in your hand for 1-2 minutes before dosing takes the edge off the cold without compromising stability
They will also review your complete medication list, as drug interactions or other medications may contribute to musculoskeletal symptoms
For example, the STEP 1 trial of once-weekly semaglutide (2.4 mg) in people without diabetes achieved a ~15% average body weight reduction over 68 weeks (source), with a mean baseline BMI of ~38 (source)
If you experience tiredness while taking a GLP-1 medication, several strategies may help manage this symptom while maintaining the therapeutic benefits of treatment
Because of its triple-action mechanism, it appears to have a broader metabolic impact compared with traditional GLP-1 agonists like Wegovy and Mounjaro