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Dose escalation should follow licensed schedules to minimise gastrointestinal adverse effects

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Aging Cell (2017) 16:83746

The expression of COX-2 mRNA in dentate gyrus granule cells is significantly upregulated, and morphological changes associated with cell death are observed in rats following intrahippocampal injection of colchicine

The CRT and HSP90 levels were upregulated after the ZFPG, ZFP + US, and ZFPG + US treatments, as indicated by the CRT and HSP90 fluorescence staining images of tumor sections after different treatments

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