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This probe is suitable for in vivo use to specifically and transiently label dying photoreceptors, such as in living rats with retinal degeneration the Royal College of Surgeons rat model, in a non-invasive and non-toxic method without the need of intraocular injection 36

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Another study published by Diabetes, Obesity & Metabolism in June 2025 further supported this link, concluding that the five-year risk of developing NAION doubled in patients using GLP-1 drugs compared to non-users

However, in authors clinical judgement, this tissue can be converted into a flap to close the nasal floor, thus precluding the need for any vestibular releasing incision