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These migrating or circulating tumor cells are exposed to various physical cues, including interstitial fluid pressure, matrix stiffness, solid stress, viscoelasticity, confining 3D topographies, hydraulic resistance, extracellular fluid viscosity, and drag forces (Fig

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A key strength of this study lies in its use of diverse methodological approaches to comprehensively assess the effects of semaglutide on cognitive function and neuroprotection

As we will discuss later, this further justified the development of synthetic GLP-1/glucagon co-agonists as promising weight loss therapeutics, particularly in the context of avoiding unwanted hyperglycaemia in obesity-associated type 2 diabetes

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The restoration of adipose function not only enhances lipid clearance but also reduces hepatic steatosis and pancreatic stress, potentially explaining the improvements in liver enzymes (ALT, AST) and glucose tolerance observed in our study