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The peptide is structured with a C20 fatty diacid modification at Lys, enabling once-weekly subcutaneous dosing through albumin binding

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GLP-1 RA c chng minh c kh nng c ch s chuyn i ny thng qua nhiu con ng tn hiu, bao gm c ch NF-B v cc con ng tn hiu vim khc

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The product of the isobutyryl-CoA dehydrogenase (IBD) reaction, methacrylyl-CoA, is hydrolyzed to 3-hydroxyisobutyryl-CoA by the enzyme often identified as methacryly-CoA hydratase