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Some patients, particularly those with neurological involvement, may benefit from more frequent dosing (every 2 months rather than 3 months), but this should be medically supervised rather than self-adjusted

Both are supplied lyophilised (freeze-dried) for stability during transit

Similarly, concentrations of DMSO ranging from 0.01-1% were reported to cause hyperactivity in zebrafish larvae, with morphological abnormalities noted only at the 1% exposure group 50

Beyond Use Date Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 48 weeks from receipt

Because IV delivery achieves near-complete bioavailability by bypassing the digestive system entirely, the nutrient impact per session tends to be more comprehensive, which can extend the interval between treatments compared to single-nutrient injections

Taking a multi-vit containing iron is rarely helpful as it can block the absorption of other nutrients