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We discovered that Diphenyleneiodonium chloride (DPI), an inhibitor of flavoprotein enzymes and mitochondrial complex I, synergizes with mitoquinone mesylate (MitoQ), a mitochondria-targeted antioxidant in 2D and 3D in vitro models of NB

Liquid B12 breaks down when exposed to light, so avoid storing it in transparent ampules or syringes

Room-temperature equilibration is a small step that meaningfully protects potency

If the dilution is not correct, the run will fail suitability and well need to adjust the dilution to ensure accurate results

Cross-checking results against multiple independent groups strengthens any mechanistic claim

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