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Todays disappointing announcement on semaglutide will come as a blow for people affected by Alzheimers, said Susan Kohlhaas, PhD, Executive Director of Research and Partnerships at Alzheimers Research UK, in a press release

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We observed the dissociation of p53 TAD (13-61) from FOXO4 FHD upon the addition of p53 TAD PEP, resulting in a chemical shift of the 15 N-p53 TAD-FOXO4 FHD complex towards the unbound state of p53 TAD (Figure

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