[21] [22] Some more serious side effects include: [12] Ongoing pain that begins in the upper left or middle of the stomach but may spread to the back Vomiting Hives, rash, itching Difficulty breathing or swallowing Swelling of lips, tongue, face, or throat Vision changes Fast heartbeat Dizziness or fainting Pain in the upper stomach, fever, yellowing of skin or eyes, or clay-colored stools Other reported adverse effects of dulaglutide include a small mean increase in heart rate, small decrease in systolic blood pressure and increases in pancreatic enzymes
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He says while a plateauing of weight-loss is seen in Mounjaro (tirzepatide) at around 10-12 weeks and semaglutide plateaued at around 45-50 weeks, retatrutide showed weight-reduction benefits even after 68 weeks, the end time for the clinical trial
Richert, S., Bloom, E
Vu may begin to increase your dose after the first four weeks , with subsequent dosage increases as well
doi:10.2147/DMSO.S299558 Rasquin LI, Anastasopoulou C, Mayrin JV