The regulatory crackdown on compounding may improve access for some, but it doesn't address the broader issue: keeping patients on these medications long-term requires infrastructure that most telehealth models werent built to provide
Most people reach their target dose around week 1317
Whilst LOCF was the most commonly used method to address missing data across the trials included in the NMA, LOCF-based statistical approaches are no longer recommended due to concerns regarding the plausibility of the assumptions (ie, body weight would be unaffected by discontinuations for trial participants lost to follow-up) and the potential for bias
#Pharma has been aiming for years to achieve magnitude of #weightloss similar to #bariatricsurgery, and now multiagonists prove that can be achieved. * HOWEVER, not everyone needs bariatric surgical magnitude of wt loss (and the discontinuations due to perceived excessive wt loss in this reta trial prove this point)
Intensive Outpatient Program (IOP): The IOP level offers a balanced approach to recovery and is suitable for those who have responsibilities at home, work, or school but still require significant support
This shelf forms mainly due to scar tissue and restrictions after surgery
