21,22 They cloned and sequenced the preproglucagon gene, discovering GLP-1 and GLP-2 hormones
A paper published this week in JAMA Psychiatry found semaglutide, the active ingredient in GLP-1 drugs like Ozempic and Wegovy, "significantly improved" motivation in patients with major depressive disorder, or MDD a promising finding because lack of motivation and related disruptions to the brains reward pathways play a critical role in many other psychiatric conditions as well
The highest doses studied 8 mg and 12 mg were associated with the greatest weight loss outcomes in trial data, but also with a higher incidence of side effects
Can I travel with GLP-1 Probiotic
Early trial results In phase 2 trials, Retatrutide delivered impressive results: Mean weight reduction of up to ~17.5% at 24 weeks, rising to ~24.2% at 48 weeks in overweight/obese adults
You and your doctor make that call together, visit by visit