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10.1186/ar4405 132 LiT.ZhangH.ChanP

Figure EV2 Cycloheximide chase assay for monitoring the cellular stability of the PiP-MS hits

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To date, we have identified 25 genetically encoded selenoproteins in human, including glutathione peroxidase (GPx), thioredoxin reductase (TXNRD), and iodothyronine deiodinases (DIOs), which have a wide range of functions, from anti-inflammatory and antioxidant activities to thyroid hormone metabolism

Inhibition of GPR109A can be accomplished through the Gln metabolism/ER stress/GPR109A axis

Wiser et al., 2010