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An in vitro study using GnRH neurons of adult male mice demonstrated that both GLP-1 and Ex4 might excite GnRH neurons, either directly or indirectly by modulating the nitric oxide (NO) and endocannabinoid pathways that control the presynaptic excitatory GABA-ergic inputs to GnRH neurons [36]

When you submit your health assessment on the Trimi platform, it goes to a licensed Arora Health provider in your state

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It offers clinical evaluation and, when eligible, a prescription that may be routed toward a branded FDA-approved product or a compounded tirzepatide formulation