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Du, Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial

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Most participants find that these adjustments make the transition much smoother

This is especially noticeable in the first 24 weeks as your body adjusts to new eating patterns and hormonal signals from GLP-1 activation

Your provider can advise whether advancing your timing for a specific circumstance outweighs the minimal risk

If you are struggling with the side effects of your medication, consider these adjustments: Eat Smaller, More Frequent Meals: Since your stomach empties slowly, large meals are your enemy