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However, this should only be done by or under the supervision of a licensed medical professional to ensure its done safely and effectively.
For example, in cultured endothelial cells, lipoic acid was found to inhibit IKK-, an enzyme that promotes the translocation of redox-sensitive and pro-inflammatory transcription factor, nuclear factor-kappa B (NFB) from the cytosol to the nucleus (46)
Manufacturers compensate by using peptide fragments or lipid-conjugated peptides that absorb more readily, but these are workarounds, not solutions
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