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Comparative analysis of lipid metabolism between the HFD + EPA + L-carnitine group and the HFD group showed a significant increase in EPA (EPA was below detection limits in the HFD group), DHA and DPA and a significant decrease in arachidonate in the former group (20:4n-6) (Table 4)

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The same study found higher rates of nausea, arthritis, sleep disturbances, kidney stones, and severe gastrointestinal problems