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Use of the ergot derivative bromocriptine for lactation suppression in conjunction with a sympathomimetic (i.e., isometheptene or phenylpropanolamine) for other therapeutic uses has resulted in adverse effects such as worsening headache, hypertension, ventricular tachycardia, seizures, sudden loss of vision, and cerebral vasospasm

medRxiv 2020: 2020.2010.2007.20208702

Specifically, a 20-50% fall in consumption of fresh fruits and vegetables has been noted

In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]

1.9- structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications Biochemistry 1991