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Collectively, these findings demonstrate sustained Exe4 expression and secretion by the liver following a single in vivo genome editing at the mouse Alb locus using LNP-mediated HITI, with no discernible side effects

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Glycemic Control In patients with type 2 diabetes, the 2.02 percentage point HbA1c reduction at 36 weeks is among the largest reported for any single agent in this patient population [8]

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Studies indicate that compounds should be stored at 4C or colder, protected from light upon receipt to prevent degradation