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Expression of stress response genes is delayed in Gstp1/2 / mice after PH / ROS modulate MAPK activation such as JNK, which is essential for regulating the intracellular redox status and the balance between cell proliferation and cell death
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Profound lesions resulting in the death of parenchymal cells and inflammation instigate reactive astrogliosis that forms a border between damaged non-neural lesion core and surrounding neural tissue
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