GHK-Cu vs other anti-aging approaches How copper peptides compare
Intravenous use can be very effective, and doesn't cause diarrhea by this route, but this agent must be given extremely carefully, since an error in dosing can shut down the bone marrows production of blood cells, and potentially be fatal
10.1007/s00438-004-1006-8 Mol
Each 1 mL (100 units on a standard insulin syringe) delivers 5 mg of epitalon

Compound Overview Class of Compound: Peptide Mechanism of Action: Epithalon upregulates telomerase activity and elongates telomeres, with the effect of delaying aging processes in reproductive and immune systems and increasing the longevity of test subjects Notable Studies: Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells AEDG Peptide (epitalon) stimulates gene expression and protein synthesis during neurogenesis: possible epigenetic mechanism Peptides and CCL11 and HMGB1 as molecular markers of aging: literature review and own data Also Known As: Epitalon, 307297-39-8, Epithalone, UNII-O65P17785G, O65P17785G, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-glycine acetic acid Research Applications: Anti-aging & longevity Sleep enhancement Disease prevention Risks: Injection site pain Lack of FDA approval Research concentrated in one group Chemical Structure What is Epithalon

This is most likely attributed to the inability of the constrained 13- and 14-membered macrocycles to adopt the proper transition states required for cleavage of the N-terminal peptide bond (Andersson et al., 2011) (Figure 8)