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In one recent case report, an ALS patient showed clinical improvement after receiving FMT, with better scores on the ALS Functional Rating Scale and lower levels of inflammation-related markers like CRP and IL-6 (Yan et al., 2024)

10.1142/S0192415X18500714 260 WangW.-H.ChenJ.ZhangB.-R.LuS.-J.WangF.PengL.et al (2018b)

It plays a vital role in: Cellular energy production DNA repair and cellular regeneration Metabolic function Healthy ageing pathways NAD+ levels decline naturally with age, which may contribute to fatigue, reduced focus, slower recovery and reduced resilience

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Interestingly, cardiomyocyte-specific p53 ablation does not prevent DOX-induced myocardial reactive oxygen species generation, apoptosis, or fibrosis, suggesting the involvement of p53-independent pathways [95]

however, meta-analyses reveal regional differences in its association with AD risk, underscoring the need for further investigation [70]