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The peptide has demonstrated cytoprotective effects against NSAIDs, alcohol, and various toxic agents in gastrointestinal studies
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Severe kidney disease, where dosing should be monitored because the kidneys clear excess B12
GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice