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Similar content being viewed by others Introduction Individuals with type 2 diabetes (T2D) face a heightened risk of cardiovascular and cerebrovascular (CV) events, alongside increased mortality

CYP7A1 is the rate-limiting enzyme in converting cholesterol to bile acids, and LXRs, which function as cholesterol sensors, increase Cyp7a1 expression in response to acute cholesterol intake in mice [2,33]

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rat CHOP (Gene Bank Accession No NM_001109986.1) forward primer (F: 5-CTGCCTTTCACCTTGGAGAC-3) and reverse primer (R: 5-CGTTTCCTGGGGATGAGATA-3)