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These findings suggest that while bitter substances promise to improve glucose homeostasis, their potential adverse effects beyond the gastrointestinal system warrant careful consideration [196]

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Stay Hydrated: GLP-1s can reduce thirst, increasing the risk of dehydration

Comparison of treatments was performed on a within-subject level (each mouse was its own control) and at least 1 week elapsed between each testing condition (drug or control treatment)

Stimulation of these receptors, expressed in a wide range of tissues, including the pancreas, liver, gastrointestinal tract, kidneys, heart, endothelium, muscles, and brain, mediate multiple effects on the body

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