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Due to the observational study design, an inherent limitation was residual confounding by unmeasured confounders such as household annual income and other socioeconomic status, which might affect choice of diabetes medications and development of AF

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Currently, numerous patients with such chronic degenerative diseases may benefit from effective long-term pharmacological treatments

Occasionally, goiter is not clinically detectable, but may be seen only with computed tomography or ultrasound examination of the thyroid

In the U.S., an estimated 178,000 deaths per year are attributed to alcohol consumption, and 2.6 million deaths annually worldwide

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