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These include how long the ulcer has been present, if the wound is infected, a Wagner grade 4 or higher, limited blood flow to the extremities, an unusually high protein level in the urine, an infection in the bone, and a higher than normal white blood cell count

Reinforcing this trend, a recent casecontrol study emphasized a robust inverse connection between adiponectin and T scores in women with osteoporosis and osteopenia [93]

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