Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study
doi: PubMed: 17450150
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This approach significantly increases the bioavailability of the drug when taken orally
25,26 This was primarily because the CEA was undertaken shortly after the products market launch, before real-world treatment patterns could be estimated, and because retreatment had not been investigated in clinical trials, leaving the effect of reinitiation uncertain