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Time-course analysis confirmed that ACh-induced hyperemia was attenuated in KD mice compared to WT controls (Fig

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Specifically, beyond the enteroendocrine L-cells of the intestine, GLP-1 is also produced as a neuropeptide by the pre-proglucagon neurons in the brain stem 3

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Oral estrogen is thought to undergo first pass hepatic metabolism resulting in activation of the renin angiotensin aldosterone system which subsequently increases levels of angiotensin II